In Vivo Quantification of Aortic Stiffness in Abdominal Aortic Aneurysm Patients using MR Elastography: A Longitudinal Study
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Date
2019-03
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Abstract
Abdominal aortic aneurysm (AAA) rupture causes death in 90% of AAA patients. Clinically, the rupture potential is evaluated using AAA diameter. Aortic stiffness can potentially provide more accurate rupture risk assessment. Therefore, the aim of this study is to use non-invasive MR elastography (MRE) to estimate aortic stiffness in AAA patients, and study the relationship between stiffness and AAA diameter. Results showed that aortic stiffness varied during the serial follow-up, demonstrating (1) no correlation between AAA stiffness and diameter, and (2) AAA diameter may not be an accurate indicator for rupture potential.
Description
Engineering: 1st Place (The Ohio State University Edward F. Hayes Graduate Research Forum)
Keywords
MR Elastography, MRI, Abdominal Aortic Aneurysm, Aortic Stiffness, Rupture Prediction, Cardiovascular MRE
Citation
Dong H, Raterman B, Mo X, Kalra P, White RD, Kolipaka A. In Vivo Quantification of Aortic Stiffness in Abdominal Aortic Aneurysm Patients using MR Elastography: A Longitudinal Study. In: Sci Meet Int Soc Magn Reson Med. ; 2018. Dong H, Mazumder R, Illapani VSP, Mo X, White RD, Kolipaka A. In vivo quantification of aortic stiffness using MR elastography in hypertensive porcine model. Magn Reson Med. 2017;78(6):2315-2321. doi:10.1002/mrm.26601.