Knowledge Bank

Vibrational circular dichroism (VCD) spectra of (S)-4-benzyl-2-oxazolidinone in $CDCI3$ in the C-H, N-H, and $C=O$ stretching and C-H and N-H bending regions will be presented. All VCD spectra show a distinct bias. Analysis of these spectra, based on an application of the ring current mechanism, leads to the determination of the conformation of this molecule in solution. Only one ring conformation is consistent with the sign of the VCD signal in all spectral regions.