STUDYING THE STEREOCHEMISTRY OF NAPROXEN USING ROTATIONALLY RESOLVED ELECTRONIC SPECTROSCOPY.

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Abstract

Many biochemical processes are stereospecific. An example is the physiological response to a drug that depends on its enantiomeric form. Naproxen is a drug which shows this stereo-specific physiological response. To better understand the stereo specificity of chiral substances, we observed the S$_1\leftarrow$S$_0$ transitions of R- and S-naproxen in the gas phase using rotationally resolved electronic spectroscopy. The results will be discussed.

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Work supported by NSF (CHE-0615755)
Author Institution: Department of Chemistry, University of Pittsburgh, PA 15260

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