Is there a Relationship between HDL Cholesterol and Muscle Mass in Post-Menopausal Women?
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Date
2014-05
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Publisher
The Ohio State University
Abstract
Menopause coincides with undesirable changes in body composition including increased fat mass and loss of muscle mass (1). One contributing factor to muscle loss is sarcopenia, a low muscle for weight medical condition. These changes are closely linked with enhanced risk for cardiovascular diseases, the top killer of postmenopausal women in the United States. High-density lipoprotein cholesterol (HDL-C), often called the “good cholesterol”, predicts for protection against cardiovascular disease in women. Mouse studies have shown that higher HDL-C levels are positively correlated with higher lean body mass (2). The relationship of HDL-C levels and muscle mass in overweight, Type 2 diabetic, postmenopausal women at risk for cardiovascular diseases was examined. The results indicated that higher levels of total body fat correlate strongly with increasing trunk fat, however, higher HDL-C levels did not correlate with greater lean body mass.
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Keywords
HDL, Cholesterol, Adipose, Menopause