FOURIER TRANSFORM INFRARED VIBRATIONAL CIRCULAR DICHROISM OF SUGARS AND NUCLEIC ACIDS

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1984

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Ohio State University

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We have undertaken a series of vibrational circular dichroism (VCD) measurements on sugars and nucleic acids employing a FTIR spectrometer. A correlation relating the sequential arrangement of hydroxyl groups to the sign of a VCD band near $1100 cm^{1}$ is noticed from these studies. Also the VCD of 6-deoxy galactose in $1600-1300 cm^{-1}$ region has revealed a correlation relating the orientation of the methyl group at $C_{6}$ with respect to that of methine group at $C_{1}$. These new results and their useful implications will be discussed.

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Author Institution: Department of Chemistry, Vanderbilt University

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