ON THE ADVANTAGES OF MATRIX-ISOLATION VIBRATIONAL CIRCULAR DICHROISM SPECTROSCOPY

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Date

2006

Authors

Tarczay, György
Magyarfalvi, Gábor
Vass, Elemér

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Ohio State University

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Abstract

It is shown on the examples of R-2-amino-1-propanol }, in press 2006.} and N-acetyl-L-alanyl-N-methylamide } that matrix isolation vibrational circular dichroism spectroscopy is a useful method for simultaneous determination of the conformational distribution and absolute configuration of molecules with multiple conformers capable of strong intermolecular interactions, especially hydrogen-bonds. The technique could also be utilized for the characterization of reactive chiral species or weakly bound complexes of chiral molecules.

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Author Institution: Institute of Chemistry,; Eotvos University,; H-1518 Budapest 112, P.O. Box 32, Hungary

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