A Worksite Translation of the Diabetes Prevention Program among Employees with Prediabetes

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INTRODUCTION: Type 2 diabetes mellitus (T2DM) is a serious medical condition affecting over 12% of Americans and is associated with $58 billion in work-related annual costs. Prediabetes increases risk for T2DM, and is estimated to affect over one third of U.S. adults. There is an evident need to prevent the development of T2DM in at-risk individuals. Adults spend a significant portion of their time at the workplace, suggesting its utility for efforts at health promotion and disease prevention. The Diabetes Prevention Program (DPP) is a lifestyle intervention program that has demonstrated efficacy in preventing or delaying T2DM in at-risk adults, however there is a lack of well-designed research studies evaluating the efficacy of the DPP in the workplace. The primary aim of this study was to implement and evaluate the efficacy of the group-based DPP intervention at The Ohio State University (OSU). METHODS: Seventy-eight employees with prediabetes recruited from OSU were randomized to the 16-week group-based DPP intervention group or a usual care control group. Sixty-eight participants completed data collection at baseline and post-intervention. Clinical and anthropometric measures included body weight, waist circumference, fasting blood glucose and lipids, and blood pressure. Statistical analyses included Pearson chi-square tests for baseline demographic characteristics and Student t-tests within an ANOVA for between and within-group analyses. For data not meeting normality assumptions, Wilcoxon signed rank tests were used for within-group and Wilcoxon rank sum 2-sample test for between-group comparisons. Multivariate analyses between variables were completed using Spearman nonparametric correlations. RESULTS: There were no significant differences in primary outcomes between treatment groups at baseline except for occupation. Mean (±SE) change in body weight for experimental versus control groups was -5.25 kg (±0.55) vs. -0.37 kg (±0.56), (p<0.0001). Fasting glucose was reduced by a mean (±SE) of -8.56 mg/dL (±1.52) and -4.48 mg/dL (±1.79), (p=0.0293), for the experimental versus control groups, respectively. CONCLUSIONS: The worksite was an effective setting to implement the DPP intervention, and facilitated significant reductions in body weight and blood glucose. Evaluation of cost-effectiveness of the intervention for employers and long-term maintenance of weight loss and prevention of T2DM are warranted.


Education and Human Ecology: 3rd Place (The Ohio State University Edward F. Hayes Graduate Research Forum)


Worksite, Prediabetes, Nutrition, Diabetes prevention program