Keto Prescribed: Translating Ketogenic Research into Clinical Practice in Adult African American Women
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Date
2020-05
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The Ohio State University
Abstract
Background: In 2016, cardiovascular disease (CVD) in the United States cost the U.S. 555 billion U.S. dollars and is projected to cost over 1.1 trillion U.S. dollars by 2035. CVD is the leading cause of death in the United States. CVD kills about 647,000 Americans each year, which is more than cancer and chronic lung disease combined. Currently, many women may die before they have symptoms or see a health care professional.
Purpose: The goal of the Keto Prescribed EBP project was to evaluate the implementation of the ketogenic diet on cardiovascular risk factors and health-related quality of life in Africa American women.
Methods: A combination of in-person group coaching sessions, and online video education sessions, integrating technology, was used to deliver ketogenic diet education to participants in the project.
Results: Of the total enrolled participants (n=5), data were collected at baseline and 22 days for four remaining participants. Results indicated that: weight, BMI and diastolic blood pressure decreased among all participants; waist to hip ratio (WHR) decreased in 75% of participants and remained the same for one; systolic BP increased for 50% (n=2) participants; and systolic BP decreased for 50% (n=2). Blood ketones at two static time points increased in participants. Health-Related Quality of Life (HRQoL) outcomes showed 75% (n=3) of participants self-reported improvement in general health (GH), and 50% (n=2) reported mental health (MH) improvements.
Conclusions: The goal of the Keto Prescribed (KRx) EBP project was to implement research evidence and evaluate the outcomes of ketogenic eating on cardiovascular risk factors and health-related quality of life in Africa American women. Limitations of this project include a very small number of participants, however, on-going evaluation with additional women is taking place. Ad hoc conversations with participants suggest that relationship and accountability factors help participants with engagement. The project suggests a need for further evidence-based practice implementation of ketogenic nutritional therapy combined with psychological education components in real-world clinical settings. The Keto Prescribed EBP project presents a nurse practitioner led interprofessional well-care model approach as a viable option for community interventions among African American women to improve CVD risk. However, further research is needed.
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Keywords
CVD risk, Ketogenic diet, African American women, Cardiovascular disease risk, weight loss, Cardiovascular disease