Magnetic Wire Traps and Programmable Manipulation of Biological Cells

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fac_VieiraG_PhysicalReviewLetters_2009_103_12.pdf (643.87 KB)

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2009-09-17

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American Physical Society

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We present a multiplex method, based on microscopic programmable magnetic traps in zigzag wires patterned on a platform, to simultaneously apply directed forces on multiple fluid-borne cells or biologically inert magnetic microparticles or nanoparticles. The gentle tunable forces do not produce damage and retain cell viability. The technique is demonstrated with T-lymphocyte cells remotely manipulated (by a joystick) along desired trajectories on a silicon surface with average speeds up to 20 μm/s.

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G. Vieira et al, "Magnetic Wire Traps and Programmable Manipulation of Biological Cells," Physical Review Letters 103, no. 12 (2009), doi:10.1103/PhysRevLett.103.128101

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http://hdl.handle.net/1811/48119

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Ohio State University Research and Scholarship