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Development of Proteolysis Targeting Chimeras as a Target for Hepatocellular Carcinoma
Rozenberg, Galina; Tokarski, Bo; Coss, Christopher (2020-11)
Proteasomes are novel targets for cancer treatments and can be used for targeted protein degradation. Proteolysis-Targeting Chimeras, or PROTACs, contain a region that binds to a target protein linked to a hydrophobic tag ...