RSS 2.02020 Autumn Undergraduate Research Festival
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Characterizing the Role of Novel FGFR2 Alterations in Cholangiocarcinoma
Patel, Avni ( 2020-11 )Affecting approximately 8,000 individuals annually, intrahepatic cholangiocarcinoma is an aggressive bile duct cancer that has a poor prognosis and slim survival rate. Alterations in the fibroblast growth factor receptor ... -
Hyperoxia-induced lung engraftment of human cord blood monocytes in a humanized mouse model of bronchopulmonary dysplasia
Reddy, Priya ( 2020-11 )Background: Bronchopulmonary dysplasia (BPD) is most often characterized by chronic lung injury secondary to high levels of oxygen during the neonatal period. Properties of the preterm infant during the perinatal period, ... -
Development of Proteolysis Targeting Chimeras as a Target for Hepatocellular Carcinoma
Rozenberg, Galina; Tokarski, Bo; Coss, Christopher ( 2020-11 )Proteasomes are novel targets for cancer treatments and can be used for targeted protein degradation. Proteolysis-Targeting Chimeras, or PROTACs, contain a region that binds to a target protein linked to a hydrophobic tag ... -
Cre-lox mediated conditional removal of myeloid cell-derived Mif in a mouse model of oral cancer.
Siddiqui, Arham ( 2020-11 )Oral cancer affects people globally with an estimated 657,000 new cases and 330,000 deaths yearly. Macrophage migration inhibitory factor (Mif) is a gene that encodes for a cytokine involved in regulating cell-mediated ... -
Optimization of Palladium Promoted Transition Metal Catalysts for Lean Methane Oxidation
Wynne, Brian ( 2020-11 )The substantial increase in greenhouse gases in the atmosphere has been linked to global warming. Although carbon dioxide (CO2) has the largest contribution to the increase in the Earth's temperature, methane (CH4) has a ...