Ibrutinib enhances IL-17 response by modulating the function of bone marrow derived dendritic cells
Natarajan, Gayathri (2015-02)
Ibrutinib (PCI-32765) is an irreversible dual Btk/Itk inhibitor shown to be effective in treating several B cell malignancies. However, limited studies have been conducted to study the effect of this drug on myeloid cell ...
THE EFFECT OF PHOSPHORYLATION OF MOUSE SAMHD1 ON RESTRICTION OF HIV-1 AND MURINE LEUKEMIA VIRUS INFECTIONS
Wang, Feifei (2015-02)
Background: The dNTPase SAMHD1 functions as an HIV-1 restriction factor in non-dividing cells by limiting intracellular dNTP levels required to complete viral reverse transcription. Phosphorylation of human SAMHD1 (hSAMHD1) ...