The Transient-Zone in the Human and Mouse Adrenal Gland
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Citation:The Ohio Journal of Science. v72 n2 (March, 1972), 120-126
The use of histological criteria to classify the stages in development of the transientzone in the human and mouse adrenal gland may elucidate the question of structural and functional homology. The transient-zone differs in its development and probable function in these two mammalian species in three ways. (1) With respect to time of appearance and disappearance, the transient-zone develops in man during the fourth week of gestation (Stage 1) and disappears from 28 weeks gestation to one year postnatal (Stage 4). In the mouse the transient-zone appears during the eight postnatal day (Stage 1) and disappears in the male at the onset of puberty and in the female during the first pregnancy (Stage 4). (2) With respect to PAS-positive material, in 18-week-old human fetuses (Stage 3), juxtanuclear PAS-positive coarse granules surrounding a homogeneous cytoplasmic mass may represent the Golgi region. The presence of this material is not demonstrated in the mouse. (3) With respect to lipid and cholesterol, a positive but slight reaction for lipid and a questionable reaction for the presence of cholesterol is seen in the transient-zone of man. In the mouse a positive reaction for lipid and cholesterol was never observed.
Author Institution: Department of Anatomy, College of Medicine, The Ohio State University, Columbus, Ohio 43210, and Department of Biology, Capital University, Columbus, Ohio 43209
Rights:Reproduction of articles for non-commercial educational or research use granted without request if credit to The Ohio State University and The Ohio Academy of Science is given.
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