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dc.contributor.advisorBielefend, Eric C.
dc.creatorNeel, Marie
dc.date.accessioned2012-05-24T17:43:41Z
dc.date.available2012-05-24T17:43:41Z
dc.date.issued2012-06
dc.identifier.urihttp://hdl.handle.net/1811/51879
dc.description.abstractExposure to loud noise causes trauma to the outer hair cells (OHC), which improve hearing sensitivity and frequency discrimination. The damage done can be permanent causing a significant hearing loss. Detecting noise-induced hearing loss (NIHL) early is crucial for hearing conservation programs. The current study was undertaken as part of a larger study that looks at forward masking (FWM) of the rat auditory brainstem response (ABR). FWM causes a change in ABR response by delivering a masker sound earlier in time than the probe signal. Death of OHC creates marked changes in FWM patterns. The current study assessed FWM of the latency of wave I of an ABR wave and how it changes with NIHL due to damage to the OHC. Nine Sprague-Dawley rats were tested before and after extreme noise exposure. Probe signals at 7 kHz were used to elicit the ABR. A FWM tone was played for 40 ms followed by silence for 5 ms then a 1 ms tone burst. The Sprague-Dawley rats were then exposed to a noise band ranging from 5-10 kHz at a level of 115 dB for 90 minutes. A 21 day rest period followed to ensure permanent hearing loss. The resulting ABR waves were analyzed to calculate wave I latencies. The results demonstrated that the FWM induced a prolongation of latency in an intensity-dependent fashion. An on-frequency FWM induced linear prolongation of latency, while the off-frequency FWM required much higher levels to induce prolonged latencies. Noise exposure rendered the off-frequency masking much more linear, and similar to the on-frequency masking effects. The work suggests that latency of the ABR wave I is affected by FWM, and behaves in a manner similar to ABR amplitudes for both on- and off-frequency maskers, and before and after noise exposure.en_US
dc.description.sponsorshipArts and Science Research Scholarshipen_US
dc.description.sponsorshipSBS Research Granten_US
dc.language.isoen_USen_US
dc.publisherThe Ohio State Universityen_US
dc.relation.ispartofseriesThe Ohio State University. Department of Speech and Hearing Science Undergraduate Research Theses; 2012en_US
dc.subjectForward Maskingen_US
dc.subjectOuter Hair Cellsen_US
dc.subjectAuditory Brainstem Responseen_US
dc.subjectNoise-Induced Hearing Lossen_US
dc.titleAssessing Noise Induced Changes in Forward Masking of Wave I Latencyen_US
dc.typeThesisen_US
dc.description.embargoNo embargoen_US


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