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dc.creatorMata, S.en_US
dc.creatorCabezas, C.en_US
dc.creatorVarela, M.en_US
dc.creatorPena, I.en_US
dc.creatorNino, A.en_US
dc.creatorLopez, J. C.en_US
dc.creatorAlonso, J. L.en_US
dc.creatorGrabow, J.-U.en_US
dc.date.accessioned2011-07-12T17:26:17Z
dc.date.available2011-07-12T17:26:17Z
dc.date.issued2011en_US
dc.identifier2011-RC-07en_US
dc.identifier.urihttp://hdl.handle.net/1811/49295
dc.descriptionAuthor Institution: Grupo de Espectroscopia Molecular (GEM). Edificio Quifima. Laboratorios de Espectroscopia y Bioespectroscopia. Parque Cientifico. Universidad de Valladolid, 47011 Valladolid. (Spain); Gottfried-Wilhelm-Leibniz-Universitat, Institut fur Physikalische Chemie \& Elektrochemie, Callinstrasse 3A, 30167 Hannover, Germanyen_US
dc.description.abstractA solid sample of Vitamin C (m.p. 190 $^irc$C) vaporized by laser ablation has been investigated in gas phase and characterized through their rotational spectra. Two spectroscopy techniques has been used to obtain the spectra: a new design of broadband chirped pulse Fourier transform microwave spectroscopy with in-phase/quadrature-phase-modulation passage-acquired-coherence technique (IMPACT) and conventional laser ablation molecular beam Fourier transform microwave spectroscopy (LA-MB-FTMW). \textbf{11},617-627 (2009)and references therein} Up to now, two low-energy conformer have been observed and their rotational constants determined. Ab initio calculations at the MP2/6-311++G (d,p) level of theory predicted rotational constants which helped us to identify these conformers unequivocally. Among the molecules to benefit from the LA-MB-FTMW technique there are common important drugs never observed in the gas phase through rotational spectroscopy. We present here the results on acetyl salicylic acid and acetaminophen (m.p. 136 $^irc$C), commonly known as aspirin and paracetamol respectively. We have observed two stable conformers of aspirin and two for paracetamol. The internal rotation barrier of the methyl group in aspirin has been determined for both conformers from the analysis of the A-E splittings due to the coupling of internal and overall rotation.en_US
dc.language.isoenen_US
dc.publisherOhio State Universityen_US
dc.titlePROBING VITAMINE C, ASPIRIN AND PARACETAMOL IN THE GAS PHASE: HIGH RESOLUTION ROTATIONAL STUDIESen_US
dc.typeArticleen_US


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