Feasibility of Translating Laboratory Findings into Dietary Routines: Omega-3 Fatty Acids Regimen in High Risk Breast Cancer Women
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Publisher:The Ohio State University
Series/Report no.:The Ohio State University. College of Nursing Undergraduate Research Theses; 2011
Family history, abnormal pathology related to breast biopsy, and/or personal history of breast cancer are factors that place women at highest risk for breast cancer development. Animal studies using omega 3 fatty acid supplementation have demonstrated a protective effect on breast tissue. At this institution, an IRB-approved study is ongoing to measure the effects of increased dietary intake of fish rich in omega 3 fatty acids versus omega 3 supplementation on breast adipose and serum fatty acid profiles. As a corollary to this study, a 13-item self-report questionnaire was developed for administration at the end of the study period to measure patient-reported outcomes, patient patterns and overall patient satisfaction with the intervention. The objective of this questionnaire was to evaluate the patients’ perspectives of their participation in the study and how likely they might be to continue the proposed regimen given positive study outcomes. Interim examination of the data demonstrated complaints of brief periods of symptoms, such as ‘upset stomach’ and ‘headache’ among the first participants to complete the study. Several participants reported a feeling of accomplishment. When asked if they could sustain a diet with multiple servings of omega 3 rich fish per week, participants indicated that it would be difficult. Innovative recipes or inclusion of formal dietary guidance may be helpful. These limited findings address the importance of patient-reported outcomes that may help individualize and tailor preventive interventions into daily living.
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