Magnetic Wire Traps and Programmable Manipulation of Biological Cells
Hauser, A. J.
Yang, F. Y.
Chalmers, J. J.
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Publisher:American Physical Society
Citation:G. Vieira et al, "Magnetic Wire Traps and Programmable Manipulation of Biological Cells," Physical Review Letters 103, no. 12 (2009), doi:10.1103/PhysRevLett.103.128101
We present a multiplex method, based on microscopic programmable magnetic traps in zigzag wires patterned on a platform, to simultaneously apply directed forces on multiple fluid-borne cells or biologically inert magnetic microparticles or nanoparticles. The gentle tunable forces do not produce damage and retain cell viability. The technique is demonstrated with T-lymphocyte cells remotely manipulated (by a joystick) along desired trajectories on a silicon surface with average speeds up to 20 μm/s.
Rights:©2009 The American Physical Society
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