Increased IL-12 induced STAT-4 signaling in CD8 T cells from aged mice
Rottinghaus, Erin (2008-04)
Aging is associated with poor immune function leading to increased susceptibility to infectious diseases and the development of immune associated disorders. Specific deficiencies in CD4 T cell function have been identified ...
Heterogeneity and Pliability of Tumor-educated Macrophages
Roberts, Ryan (2008-04)
Cancerous tumors survive, in part, by learning to manipulate the cells around them. Many tumors stimulate one type of white blood cell, the macrophage, to adopt behaviors that facilitate tumor growth and metastasis. Our ...