Effect of Stannous Fluoride and Iodine on Root Caries and Bone Loss in Rats
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Citation:The Ohio Journal of Science. v88, n3 (June, 1988), 99-100
Rice rats were distributed by littermate into four experimental groups as follows: stannous fluoride (0.4%), iodine-sodium iodide (1.0%), a combination of iodine-sodium iodide and stannous fluoride, and a distilled water control. Each rat was treated by swabbing the molar teeth daily. All rats were fed diet 2000 and double-distilled water ad libitum, and were sacrificed after 9 weeks. Root surface caries and bone loss were determined. Root surface caries was significantly (P < 0.05) inhibited by stannous fluoride and the combination of iodine-sodium iodide and stannous fluoride, but was not affected significantly by iodinesodium iodide alone. On the other hand, bone loss scores were significantly lower in all groups compared to the demineralized water control.
Author Institution: The Ohio State University, College of Dentistry
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