The Effect of Immune Serum on the Infectivity of Sonically Damaged Plasmodium berghei Infected Erythrocytes
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Citation:The Ohio Journal of Science. v85, n3 (June, 1985), 101-103
The reduction in the infectivity of those Plasmodium berghei containing erythrocytes which remained unlysed following exposure to sonic energy and treatment with immune serum was shown to be far greater than that caused by the sum of the separate actions of immune serum and sonic energy applied separately. This indicates that, after exposure to sonic energy, plasmodia in surviving, parasitized erythrocytes are more susceptible to neutralization by immune serum than are plasmodia in unsonicated, parasitized erythrocytes. The membranes of parasitized erythrocytes that survive sonication thus appear to be permeable so that intracellular parasites are accessible to antibodies in immune serum.
Author Institution: Department of Microbiology, The Ohio State University
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