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dc.creatorClarkson, Jasper R.en_US
dc.creatorDian, Brian C.en_US
dc.creatorZwier, Timothy S.en_US
dc.date.accessioned2006-06-15T20:51:43Z
dc.date.available2006-06-15T20:51:43Z
dc.date.issued2004en_US
dc.identifier2004-RG-12en_US
dc.identifier.urihttp://hdl.handle.net/1811/21322
dc.descriptionAuthor Institution: Department of Chemistry, Purdue Universityen_US
dc.description.abstractStimulated emission pumping (SEP)-hole filling spectroscopy and SEP-induced population transfer spectroscopy (PTS) have been used to place narrow bounds on the energy thresholds for isomerization between individual reactant-product isomer pairs. SEP-PTS is used to place upper and lower bounds to the barrier heights for various isomer pairs. The thresholds for $X \rightarrow Y$ and $Y \rightarrow X$ isomerization are combined to determine the relative energies of the X and Y minima. The combined data from all $X\rightarrow Y$ isomerizations identify important isomerization pathways on the potential energy surface linking the minima. Application of the aforementioned techniques to several tryptophan analogues, including tryptamine (3-indole ethylamine), 3-indole propionic acid, and melatonin (5-methoxy tryptamine) are presented. Comparison of experimental data to ab initio computed barriers will be made, and the use of the method to test RRKM rate theory applied to conformational isomerization will be discussed.en_US
dc.format.extent314948 bytes
dc.format.mimetypeimage/jpeg
dc.language.isoEnglishen_US
dc.publisherOhio State Universityen_US
dc.titleSTIMULATED EMISSION PUMPING POPULATION TRANSFER AND HOLE FILLING SPECTROSCOPIES: NEW PROBES OF THE ENERGETIC THRESHOLDS TO CONFORMATIONAL ISOMERIZATION II. RESULTS ON ISOLATED, FLEXIBLE BIOMOLECULESen_US
dc.typearticleen_US


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