INTERNAL HYDROGEN BONDING IN CYCLIC AMIDES
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Publisher:Ohio State University
This preliminary work will discuss the effects of internal or intramolecular hydrogen bonding on the vibrational dynamics and force fields of cyclic amides. These species are being studied via i.r. and Raman spectroscopy, classical normal mode calculations and MNDO calculations. The compound of greatest interest is N-(2-hydroxyethyl)-2-pyrrolidinone (HEP), a five-membered cyclic amide. Preliminary i.r. results indicate the presence of internal hydrogen-bonding in HEP, and thus, an additional ``ring'' which is seven-membered. Computations focus on the effects of the internal hydrogen bonding upon the normal modes associated with the amide group and subtler effects within the rest of the compound. Preliminary results will be presented and contrasted with other similar work on related cyclic amides.
Address of McDermott and Meier: Department of Chemistry, Lafayette College, Easton, PA 18042, USA.