OSU Navigation Bar

The Ohio State University University Libraries Knowledge Bank

The Effect of Immune Serum on the Infectivity of Sonically Damaged Plasmodium berghei Infected Erythrocytes

Please use this identifier to cite or link to this item: http://hdl.handle.net/1811/23070

Show full item record

Files Size Format View
V085N3_101.pdf 291.0Kb PDF View/Open

Title: The Effect of Immune Serum on the Infectivity of Sonically Damaged Plasmodium berghei Infected Erythrocytes
Creators: Alder, J. D.; Kreier, Julius P.
Issue Date: 1985-06
Citation: The Ohio Journal of Science. v85, n3 (June, 1985), 101-103
Abstract: The reduction in the infectivity of those Plasmodium berghei containing erythrocytes which remained unlysed following exposure to sonic energy and treatment with immune serum was shown to be far greater than that caused by the sum of the separate actions of immune serum and sonic energy applied separately. This indicates that, after exposure to sonic energy, plasmodia in surviving, parasitized erythrocytes are more susceptible to neutralization by immune serum than are plasmodia in unsonicated, parasitized erythrocytes. The membranes of parasitized erythrocytes that survive sonication thus appear to be permeable so that intracellular parasites are accessible to antibodies in immune serum.
URI: http://hdl.handle.net/1811/23070
ISSN: 0030-0950
Bookmark and Share