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Normal Neuronal Clustering in the neck Region of the Human Gallbladder Wall and Corresponding Neuronal Denudement in Chagas Disease

Please use this identifier to cite or link to this item: http://hdl.handle.net/1811/22904

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dc.creator Conte, Vinicio P. en_US
dc.creator Pinotti, Henrique W. en_US
dc.creator Bettarello, Agostinho en_US
dc.date.accessioned 2006-07-07T02:03:49Z
dc.date.available 2006-07-07T02:03:49Z
dc.date.issued 1983-03 en_US
dc.identifier.citation The Ohio Journal of Science. v83, n1 (March, 1983), 28-30 en_US
dc.identifier.issn 0030-0950 en_US
dc.identifier.uri http://hdl.handle.net/1811/22904
dc.description Author Institution: Departrment of Gastroenterology, Surgery and Internal Medicine, University of São Paulo, Medical School en_US
dc.description.abstract Fifteen human gallbladders, 5 from normal patients (group I), 5 from Chagasic patients with cholelithiasis (group II) and 5 from Chagasic patients without cholelithiasis (group III) were studied. Perikarial counting was carried out in 3 portions of the gallbladder (neck, body and fundus), each histological sections being completely scanned and the number of nerve cells given per square millimeter. In the control group, a higher number of nerve cells is present in the neck (mean 23-45 ± 10.14) than in the body (mean 7.70 ± 8.45) and fundus (mean 5.60 ± 3.66). In the Chagasic groups with or without cholelithiasis, no nerve cells were found; few or no inflammatory cells, myositis, neuritis and perineuritis were observed in the layers of the organ. Normal gallbladders have pronounced concentration of nerve cells in the neck, compared with that of the body and fundus. Chagasic gallbladders, whether or not they are lithiasic, are completely denervated. This denervation apparently does not impair gallbladder motor function. en_US
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dc.format.mimetype application/pdf
dc.language.iso en_US
dc.title Normal Neuronal Clustering in the neck Region of the Human Gallbladder Wall and Corresponding Neuronal Denudement in Chagas Disease en_US