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Normal Neuronal Clustering in the neck Region of the Human Gallbladder Wall and Corresponding Neuronal Denudement in Chagas Disease

Please use this identifier to cite or link to this item: http://hdl.handle.net/1811/22904

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Title: Normal Neuronal Clustering in the neck Region of the Human Gallbladder Wall and Corresponding Neuronal Denudement in Chagas Disease
Creators: Conte, Vinicio P.; Pinotti, Henrique W.; Bettarello, Agostinho
Issue Date: 1983-03
Citation: The Ohio Journal of Science. v83, n1 (March, 1983), 28-30
Abstract: Fifteen human gallbladders, 5 from normal patients (group I), 5 from Chagasic patients with cholelithiasis (group II) and 5 from Chagasic patients without cholelithiasis (group III) were studied. Perikarial counting was carried out in 3 portions of the gallbladder (neck, body and fundus), each histological sections being completely scanned and the number of nerve cells given per square millimeter. In the control group, a higher number of nerve cells is present in the neck (mean 23-45 ± 10.14) than in the body (mean 7.70 ± 8.45) and fundus (mean 5.60 ± 3.66). In the Chagasic groups with or without cholelithiasis, no nerve cells were found; few or no inflammatory cells, myositis, neuritis and perineuritis were observed in the layers of the organ. Normal gallbladders have pronounced concentration of nerve cells in the neck, compared with that of the body and fundus. Chagasic gallbladders, whether or not they are lithiasic, are completely denervated. This denervation apparently does not impair gallbladder motor function.
URI: http://hdl.handle.net/1811/22904
ISSN: 0030-0950
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