OSU Navigation Bar

The Ohio State University University Libraries Knowledge Bank

The Knowledge Bank is scheduled for regular maintenance on Sunday, April 20th, 8:00 am to 8:00 pm EDT. During this time users will not be able to register, login, or submit content.

Mycobacterium Bovis (Strain BCG) Effects on the Growth and Metastasis of a Transplantable Hamster Lung Adenocarcinoma

Please use this identifier to cite or link to this item: http://hdl.handle.net/1811/22616

Show full item record

Files Size Format View
V079N3_126.pdf 321.3Kb PDF View/Open

Title: Mycobacterium Bovis (Strain BCG) Effects on the Growth and Metastasis of a Transplantable Hamster Lung Adenocarcinoma
Creators: Bakaletz, Alan P.; Zwilling, Bruce S.
Issue Date: 1979-05
Citation: The Ohio Journal of Science. v79, n3 (May, 1979), 126-130
Abstract: The effect of Bacillus-Calmette-Guerin (BCG) on the growth of an adenocarcinoma of the lung induced in a Syrian hamster was evaluated. It inhibited intradermal growth of the tumor when the tumor cells were mixed with high doses of BCG prior to intradermal injection. The development of lung metastasis after excision of the primary intradermal tumor was inhibited by BCG at doses 100 times lower than those used to inhibit the growth of intradermal tumors. The results suggest that effective immunotherapy may depend on the number of viable BCG cells, the route of administration, and the anatomic location of the tumor.
URI: http://hdl.handle.net/1811/22616
ISSN: 0030-0950
Bookmark and Share