# BIOMOLECULES IN THE GAS PHASE: THE ELECTRONIC SPECTRUM OF $MELATONIN^{a}$

Please use this identifier to cite or link to this item: http://hdl.handle.net/1811/20754

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 Title: BIOMOLECULES IN THE GAS PHASE: THE ELECTRONIC SPECTRUM OF $MELATONIN^{a}$ Creators: Yi, John T.; Applebee, Kenyon; Nguyen, Tri; Roscioli, Joseph R.; Pratt, D. W. Issue Date: 2003 Publisher: Ohio State University Abstract: Melatonin (N-acetyl-5-methoxytryptamine) is a neural hormone involved in the biochemical regulation of the circadian rhythms and other functions throughout the body. The structure is an indole derivative with a flexible peptide-like side chain, which results in many conformational structures. In this work, high resolution $S_{1} \leftarrow S_{0}$ fluorescence excitation spectra of melatonin bands have been recorded. The two observed bands of melatonin display multiple central branches, indicating two overlapping spectra. We use both the experimentally derived rotational constants and theoretical calculations to assign the conformational structures and to gain information about the nature of the molecule. The relevance of these findings will be further discussed. Description: $^{a}$ Work supported by NSF and Howard Hughes Summer Program. Author Institution: Department of Chemistry, University of Pittsburgh URI: http://hdl.handle.net/1811/20754 Other Identifiers: 2003-FC-03