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APPLICATIONS OF NEAR-INFRARED LASER SPECTROSCOPY TO BREATH ANALYSIS

Please use this identifier to cite or link to this item: http://hdl.handle.net/1811/19559

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dc.creator Sharpe, Steven W. en_US
dc.creator Blake, Thomas A. en_US
dc.creator Sams, Robert L. en_US
dc.date.accessioned 2006-06-15T19:24:08Z
dc.date.available 2006-06-15T19:24:08Z
dc.date.issued 1999 en_US
dc.identifier 1999-WG-05 en_US
dc.identifier.uri http://hdl.handle.net/1811/19559
dc.description $^{a}$ K.D. Thrall, J.J. Toth and S.W. Sharpe, SPIE Volume 2676, 136-146 (1996) en_US
dc.description Author Institution: Pacific Northwest National Laboratory, P.O. Box 999, Mail Stop K8-88, Richland, WA 99352. (PNNL is operated for the US Department of Energy by the Battelle Memorial Institute under contract DE-AC06-76RLO 1830.). en_US
dc.description.abstract Small infrared active molecules such as ammonia, carbon monoxide, carbon dioxide, methane and ethane are present in exhaled breath and can be readily detected by laser absorption spectroscopy. In addition, many of the stable isotopomers of these molecules can be accurately detected, making it possible to follow specific metabolic processes. Potential areas of applications for this technology include the diagnosis of certain pathologies (e.g. Helicobacter pylori infection), detection of trauma due to either physical or chemical causes and monitoring nutrient uptake (i.e., malnutrition). Applications of tunable infrared semiconductor lasers to breath analysis have been reported in the literature by a number of $researchers.^{a}$ Advantages of laser absorption over more conventional techniques such as Fourier transform infrared (FTIR) and non-dispersive spectrscopy include higher sensitivity, greater resolution, faster data acquisition and potentially compact packaging of the apparatus for field deployment. In this talk, we present some of our results associated with laser absorption studies on human breath and its application to diagnosis of diseases and pathologies. en_US
dc.format.extent 135233 bytes
dc.format.mimetype image/jpeg
dc.language.iso English en_US
dc.title APPLICATIONS OF NEAR-INFRARED LASER SPECTROSCOPY TO BREATH ANALYSIS en_US
dc.type article en_US