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APPLICATIONS OF NEAR-INFRARED LASER SPECTROSCOPY TO BREATH ANALYSIS

Please use this identifier to cite or link to this item: http://hdl.handle.net/1811/19559

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Title: APPLICATIONS OF NEAR-INFRARED LASER SPECTROSCOPY TO BREATH ANALYSIS
Creators: Sharpe, Steven W.; Blake, Thomas A.; Sams, Robert L.
Issue Date: 1999
Abstract: Small infrared active molecules such as ammonia, carbon monoxide, carbon dioxide, methane and ethane are present in exhaled breath and can be readily detected by laser absorption spectroscopy. In addition, many of the stable isotopomers of these molecules can be accurately detected, making it possible to follow specific metabolic processes. Potential areas of applications for this technology include the diagnosis of certain pathologies (e.g. Helicobacter pylori infection), detection of trauma due to either physical or chemical causes and monitoring nutrient uptake (i.e., malnutrition). Applications of tunable infrared semiconductor lasers to breath analysis have been reported in the literature by a number of $researchers.^{a}$ Advantages of laser absorption over more conventional techniques such as Fourier transform infrared (FTIR) and non-dispersive spectrscopy include higher sensitivity, greater resolution, faster data acquisition and potentially compact packaging of the apparatus for field deployment. In this talk, we present some of our results associated with laser absorption studies on human breath and its application to diagnosis of diseases and pathologies.
URI: http://hdl.handle.net/1811/19559
Other Identifiers: 1999-WG-05
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