OSU Navigation Bar

The Ohio State University University Libraries Knowledge Bank

Excited-State Dynamics of Pyrimidine DNA Bases Revealed by Ultrafast Vibrational Spectroscopy

Please use this identifier to cite or link to this item: http://hdl.handle.net/1811/32193

Show full item record

Files Size Format View
hayes_middleton.pdf 248.9Kb PDF View/Open

Title: Excited-State Dynamics of Pyrimidine DNA Bases Revealed by Ultrafast Vibrational Spectroscopy
Creators: Middleton, Chris
Advisor: Kohler, Bern
Issue Date: 2008-04
Abstract: To better understand the link between light absorption and deleterious DNA photoproducts, the photophysics of DNA bases was investigate with femtosecond mid-IR transient absorption spectroscopy. Markers band for two excited states, a dark singlet state and a triplet state, were found. These marker bands provide insight into the nature and dynamics of the states. The results confirm a model for pyrimidine bases previous proposed based on UV-visible transient absorption measurements. This study provides an important foundation for future investigations of the role of these states in DNA.
Citation: Patrick M. Hare, Chris T. Middleton, Kristin I. Mertel, John M. Herbert, and Bern Kohler, Chemical Physics (2008), 347, 383-392.
Embargo: A five-year embargo was granted for this item.
Series/Report no.: 2008 Edward F. Hayes Graduate Research Forum. 22nd
Keywords: DNA photophysics
time-resolved spectroscopy
excited-state dynamics
time-resolved infrared
Description: Mathematical and Physical Sciences: 3rd Place (The Ohio State University Edward F. Hayes Graduate Research Forum)
URI: http://hdl.handle.net/1811/32193
Bookmark and Share