Afferent Projections of the Clare-Bishop Area in the Cat Cortex: A Horseradish Peroxidase Study

Abstract

Recent studies of the Clare-Bishop (CB) area (the lateral suprasylvian area) have supported the role of this extrastriate, retinotopically-organized cortical region in visual and oculomotor functions. Anatomical studies were undertaken using retrograde horseradish peroxidase (HRP) techniques to define its afferent connections. Results indicate that CB receives substantial input from the ipsilateral striate and parastriate visual cortex (areas 17, 18 and 19), the contralateral CB area, claustrum, thalamus (ventral anterior nucleus, intralaminar nuclei, LP-pulvinar complex, posterior nucleus, dorsal lateral geniculate nucleus), and several brain stem nuclei (rostral linear nucleus, ventral tegmental area of Tsai, locus ceruleus, raphe nuclei). The results of the present investigation provide an anatomical substrate for the proposed role of the Clare-Bishop area in visual and oculomotor functions.